Canadian Macromolecular Crystallography Facility

Upgrade Projects

There are two technical infrastructure upgrade projects ongoing at the CMCF beamlines.

Toward Cutting-Edge Science

Establishing advanced micro-beam capability for macromolecular crystallography at the CLS

This is a CFI project led by the Beamline Advisory Team leader Mirek Cygler (U of Saskatchewan), in collaboration with other Beamline Advisory Team members and principal users representing institutes from accross Canada including: Bhushan Nagar (McGill U), Zongchao Jia (Queen's U), Filip Van Petegem (U of British Columbia), Mark Glover (U of Alberta), Kenneth Ng (U of Calgary), Brian Mark (U of Manitoba), Emil Pai (U of Toronto), Alisdair Boraston (U of Victoria) and Alba Guarné (McMaster U).

The project secured funding in 2015 (see announcement here), with the goal of upgrading the CMCF-ID beam line,  increasing the flux, reducing the beam focus size to micro-beam, improving the stability of the end-station and improving the data acquisition throughput using a faster detector and automounter.  To accomplish these goals, the undulator will be replaced with a longer one, the optical layout will be changed and the end station will be rebuilt.

The new optics, which includes a new DCM/DMM monochromator and three new mirrors, will enable the beamline to achieve a focus spot size of 5 × 30 µm with a photon-flux of about 1 × 1013 ph/s in a 5 µm focus spot, or up to 1 × 1014 ph/s in pink-beam (1% ΔE/E)  mode. Additionally, the endstation will be replaced with an MD2S microdiffractometer, while the current Pilatus 6M detector will be replaced with an Eiger 9M detector. The recently-upgraded ISARA automounter will continue to be a key component of the upgraded beamline.

As of April 2019, the preliminary design report has been completed, and all major components including the insertion device (IVU), DCM/DMM, mirror systems, microdiffractometer, and Eiger detector have been purchased, with delivery times ranging from July 2019 to May 2020.

We anticipate shutting down the CMCF-ID beamline for upgrades during the spring 2020 facility shutdown period, during which time the new insertion device will be installed, and installation of the new beamline components will begin. Commissioning is expected to last about 6 months, with an expected return to service in January 2021.  To alleviate the loss of beam time to users during this period, we will accommodate most of our users on the CMCF-BM beamline, which is also receiving a minor upgrade this spring.

CMCF-BM High-Flux Upgrade

Multi-layers for higher flux & a faster robot

This is a small project to upgrade the CMCF-BM Si-111 DCM. The goal is to add a fixed-energy high-flux mode to the beamline by adding a double-multilayer monochromator (DMM) inside the same Si-111 DCM chamber. The monochromator will operate in two modes. The DMM mode will be a pink-beam (0.45% ΔE/E),  delivering a flux of about an order of magnitude higher than the standard Si-111 mode. Experiments requiring a high energy resolution will continue to be supported with the traditional Si-111 DCM mode.

At the same time, the SAM Automounter software is being updated to support a faster throughput, with a duty cycle of about 25 seconds (currently 2.5 minutes).  

With these changes, we expect CMCF-BM users to experience a significant increase in throughput starting in July 2019. Furthermore, when the CMCF-ID beamline is shut down for upgrades, the Pilatus 6M detector will be moved permanently to CMCF-BM, further increasing the throughput. 

Installation of the equipment will be completed by the end of May 2019 after which we expect a short commissioning period before the beamline is available again for general use.





upgrade timeline