Improving antibiotics

Exploring macromolecular machines that may one day produce novel therapeutics...

Nature 529, 239-42

New take on tackling malaria

Dr. Michelle (Tonkin) Parker presented with G. Michael Bancroft Ph.D. Thesis Award at this year's AUM.

Link to related CLS story

Exploring the human microbiome

New research describes gut microorganism adaptations to yeast in the diet...

Nature 517(7533), 165-169

CMCF is an umbrella facility which operates two beamlines, 08ID-1 and 08B1-1, at the Canadian Light Source. Together, both beamlines enable high-resolution structural studies of proteins, nucleic acids and other macromolecules, satisfying the requirements of the most challenging and diverse crystallographic experiments.

  • Beamline 08ID-1 Status: Normal Operations
  • Beamline 08B1-1 Status: Normal Operations
  •               Mx School:                  May 24-28, 2016

List of Publications »

  • Getlik, Matthäus; Smil, David; Zepeda-Velázquez, Carlos; Bolshan, Yuri; Poda, Gennady; Wu, Hong; Dong, Aiping; Kuznetsova, Ekaterina; Marcellus, Richard; Senisterra, Guillermo; Dombrovski, Ludmila; Hajian, Taraneh; Kiyota, Taira; Schapira, Matthieu; Arrowsmith, Cheryl H.; Brown, Peter J.; Vedadi, Masoud; Al-awar, Rima (2016). Structure-Based Optimization of a Small Molecule Antagonist of the Int .... Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5b01630.
  • Argyropoulos, Panos; Bergeret, Fabien; Pardin, Christophe; Reimer, Janice M.; Pinto, Atahualpa; Boddy, Christopher N.; Schmeing, T. Martin (2016). Towards a characterization of the structural determinants of specifici .... Biochimica et Biophysica Acta (BBA) - General Subjects 1860(3) , 486-497. 10.1016/j.bbagen.2015.11.007. [PDB: 5d3k]
  • Das, Samir; Gilchrist, John; Bosmans, Frank; Van Petegem, Filip (2016). Binary architecture of the Na v 1.2-β2 signaling complex. eLife 5. 10.7554/elife.10960.