ISARA Sample Changer Commissioned

New CMCF-ID IRELEC ISARA sample changer used for the first time...

Samples & Automounters

MxLIVE Update

Simple, secure & streamlined sample tracking and data management...

MxLIVE User Guide Page

1000 Structures & 500 Publications!

Celebrating two milestones reached by scientists who conducted their research at the CMCF

Full CLS News Story

Tackling Autoimmune Diseases

Researchers combine CMCF-BM, CMCF-ID, SAXS & electron microscopy data to discover B-cell CD22 interaction details critical to a healthy immune response...

Nature Commun. 8, 764

Revealing Mechanisms of Biological Motors

To understand how bacteria can use pili to attach to surfaces, move themselves and become more virulent...

Nature Commun. 8, 15091

CMCF is an umbrella facility which operates two beamlines, 08ID-1 and 08B1-1, at the Canadian Light Source. Together, both beamlines enable high-resolution structural studies of proteins, nucleic acids and other macromolecules, satisfying the requirements of the most challenging and diverse crystallographic experiments.

  • Beamline 08ID-1 Status:  Normal Operations
  • Beamline 08B1-1 Status: Normal Operations

List of Publications »

  • Siu, Tony; Brubaker, Jason; Fuller, Peter; Torres, Luis; Zeng, Hongbo; Close, Joshua; Mampreian, Dawn M.; Shi, Feng; Liu, Duan; Fradera, Xavier; Johnson, Kevin; Bays, Nathan; Kadic, Elma; He, Fang; Goldenblatt, Peter; Shaffer, Lynsey; Patel, Sangita B.; Lesburg, Charles A.; Alpert, Carla; Dorosh, Lauren; Deshmukh, Sujal V.; Yu, Hongshi; Klappenbach, Joel; Elwood, Fiona; Dinsmore, Christopher J.; Fernandez, Rafael; Moy, Lily; Young, Jonathan R. (2017). The Discovery of 3-((4-Chloro-3-methoxyphenyl)amino)-1-((3R,4S)-4-cyan .... Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.7b01135. [PDB: 5wo4]
  • Wong, Alan H. M.; Tomlinson, Aidan C. A.; Zhou, Dongxia; Satkunarajah, Malathy; Chen, Kevin; Sharon, Chetna; Desforges, Marc; Talbot, Pierre J.; Rini, James M. (2017). Receptor-binding loops in alphacoronavirus adaptation and evolution. Nature Communications 8(1) . 10.1038/s41467-017-01706-x. [PDB: 6atk]
  • Scally, Stephen W.; Murugan, Rajagopal; Bosch, Alexandre; Triller, Gianna; Costa, Giulia; Mordmüller, Benjamin; Kremsner, Peter G.; Sim, B. Kim Lee; Hoffman, Stephen L.; Levashina, Elena A.; Wardemann, Hedda; Julien, Jean-Philippe (2017). Rare PfCSP C-terminal antibodies induced by live sporozoite vaccinatio .... Journal of Experimental Medicine , jem.20170869. 10.1084/jem.20170869. [PDB: 6b0s]