Researchers at U.B.C. make use of beamline 08ID-1 in their study of ryanodine receptor disease hotspots. Mutations in these hotspot regions can contribute to heart and other muscle conditions.

Nov. 27, 2010

Genetic variation in ryanodine receptor 'hotspots' can play a role in diseases affecting muscles, including congenital heart disease. Researchers from the University of British Columbia have combined crystallographic data obtained at beamline 08ID-1 and the Stanford Synchrotron Radiation Lightsource with electron microscopy data to shed light on amino-terminal ryanodine receptor disease hotspot. To view the complete media release click here. PDB ID: 2XOA.