Canadian Macromolecular Crystallography Facility

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The Immune Response

How the immune system responds to bacterial infections...

Proc. Natl. Acad. Sci. USA 115, E896

Cell Signaling

Novel therapeutic targets for cardiac disease and cancer...

Nat. Chem. Biol. 13, 757

Viral Attack Strategies

Exploring how coronavirus adapts to new situations...

Nature Commun. 8, 1735

Broad-Spectrum Antibiotic Resistance

How bacteria can inactivate certain classes of antibiotics...

Structure 25, 750

DNA Damage Repair

How cells overcome some of the toxic effects of benzopyrene...

Nucleic Acids Res. 44, 4957


CMCF is an umbrella facility which operates two beamlines, 08ID-1 and 08B1-1, at the Canadian Light Source. Together, both beamlines enable high-resolution structural studies of proteins, nucleic acids and other macromolecules, satisfying the requirements of the most challenging and diverse crystallographic experiments.


List of Publications »

  • Haji-Ghassemi, Omid; Yuchi, Zhiguang; Van Petegem, Filip (2019). The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in .... Molecular Cell 75(1) . 10.1016/j.molcel.2019.04.019. [PDB: 6mm6, 6mm7]
  • Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host Le .... Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o]
  • Aggett, Rebecca; Mallette, Evan; Gilbert, Stephanie E.; Vachon, Melody A.; Schroeter, Kurt L. et al. (2019). The steroid side chain-cleaving aldolase Ltp2-ChsH2DUF35 is a thiolase .... Journal of Biological Chemistry , jbc.RA119.008889. 10.1074/jbc.ra119.008889. [PDB: 6ok1]