Canadian Macromolecular Crystallography Facility

Arrival of New Upgrade Components

Undulator, Detector & Diffractometer arrive at CLS...

Upgrade Projects

The Immune Response

How the immune system responds to bacterial infections...

Proc. Natl. Acad. Sci. USA 115, E896

Cell Signaling

Novel therapeutic targets for cardiac disease and cancer...

Nat. Chem. Biol. 13, 757

Viral Attack Strategies

Exploring how coronavirus adapts to new situations...

Nature Commun. 8, 1735

Broad-Spectrum Antibiotic Resistance

How bacteria can inactivate certain classes of antibiotics...

Structure 25, 750

DNA Damage Repair

How cells overcome some of the toxic effects of benzopyrene...

Nucleic Acids Res. 44, 4957

CMCF is an umbrella facility which operates two beamlines, 08ID-1 and 08B1-1, at the Canadian Light Source. Together, both beamlines enable high-resolution structural studies of proteins, nucleic acids and other macromolecules, satisfying the requirements of the most challenging and diverse crystallographic experiments.

List of Publications »

  • Petrilli; Whitney L.; Adam; Gregory C.; Erdmann et al. (2020). From Screening to Targeted Degradation: Strategies for the Discovery a .... Cell Chemical Biology 26(1) , 32-40. 10.1016/j.chembiol.2019.10.002.
  • Sokaribo; AkosiereremS.; Novakovski; Brian A.A.; Cotelesage et al. (2020). Kinetic and structural analysis of Escherichia coli phosphoenolpyruvat .... Biochimica et Biophysica Acta - General Subjects 1864(4) , 129517. 10.1016/j.bbagen.2020.129517.
  • Pluvinage; Benjamin; Massel; Patricia M; Burak et al. (2020). Structural and functional analysis of four family 84 glycoside hydrola .... Glycobiology 30(1) , 49-57. 10.1093/glycob/cwz069.