Canadian Macromolecular Crystallography Facility

New CLS User Portal

A new portal with common login for training, proposal submissions and beamtime requests...

CLS User Portal

Updated Data Collection Interface!

Featuring improved crystal centering, automation & collection options plus many new features for a more efficient data collection experience...

MxDC Highlights

ISARA Sample Changer Commissioned

New CMCF-ID IRELEC ISARA sample changer used for the first time...

Samples & Automounters

MxLIVE Update

Simple, secure & streamlined sample tracking and data management...

MxLIVE User Guide Page

1000 Structures & 500 Publications!

Celebrating two milestones reached by scientists who conducted their research at the CMCF

Full CLS News Story

Tackling Autoimmune Diseases

Researchers combine CMCF-BM, CMCF-ID, SAXS & electron microscopy data to discover B-cell CD22 interaction details critical to a healthy immune response...

Nature Commun. 8, 764


CMCF is an umbrella facility which operates two beamlines, 08ID-1 and 08B1-1, at the Canadian Light Source. Together, both beamlines enable high-resolution structural studies of proteins, nucleic acids and other macromolecules, satisfying the requirements of the most challenging and diverse crystallographic experiments.


  • Beamline 08ID-1 Status:  Maintenance Mode
  • Beamline 08B1-1 Status: Maintenance Mode
  •           Mx School:            June 4 - 8

List of Publications »

  • (2018). Holding Open Micropores with Water: Hydrogen-Bonded Networks Supported .... Chem 4(4) , 868-878. 10.1016/j.chempr.2018.02.004.
  • Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent f .... Journal of Biological Chemistry , jbc.RA117.001098. 10.1074/jbc.ra117.001098. [PDB: 5ud0, 5ud1, 5ucn, 5ucp, 5ucs, 5ucz, 5ud2]
  • Crowe; Adam M.; Workman; Sean D.; Watanabe et al. (2018). IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholester .... Proceedings of the National Academy of Sciences , 201717015. 10.1073/pnas.1717015115. [PDB: 6co6, 6coj, 6con]