Canadian Macromolecular Crystallography Facility

Beam Time for COVID-19 Research

Click through for COVID-19-related beam time resources.

Arrival of New Upgrade Components

Undulator, Detector & Diffractometer arrive at CLS...

Upgrade Projects

The Immune Response

How the immune system responds to bacterial infections...

Proc. Natl. Acad. Sci. USA 115, E896

Cell Signaling

Novel therapeutic targets for cardiac disease and cancer...

Nat. Chem. Biol. 13, 757

Viral Attack Strategies

Exploring how coronavirus adapts to new situations...

Nature Commun. 8, 1735

Broad-Spectrum Antibiotic Resistance

How bacteria can inactivate certain classes of antibiotics...

Structure 25, 750

DNA Damage Repair

How cells overcome some of the toxic effects of benzopyrene...

Nucleic Acids Res. 44, 4957

CMCF is an umbrella facility which operates two beamlines, 08ID-1 and 08B1-1, at the Canadian Light Source. Together, both beamlines enable high-resolution structural studies of proteins, nucleic acids and other macromolecules, satisfying the requirements of the most challenging and diverse crystallographic experiments.

List of Publications »

  • Manenda; Mahder S.; Picard; Marie-Ève; Zhang et al. (2020). Structural analyses of the group A flavin-dependent monooxygenase PieE .... Journal of Biological Chemistry , jbc.RA119.011212. 10.1074/jbc.ra119.011212.
  • Hersch; Steven J.; Watanabe; Nobuhiko; Stietz et al. (2020). Envelope stress responses defend against type six secretion system att .... Nature Microbiology . 10.1038/s41564-020-0672-6.
  • Alonzo; Diego A.; Chiche-Lapierre; Clarisse; Tarry et al. (2020). Structural basis of keto acid utilization in nonribosomal depsipeptide .... Nature Chemical Biology . 10.1038/s41589-020-0481-5.