CANADIAN MACROMOLECULAR CRYSTALLOGRAPHY FACILITY

Mx Data Collection School

Canadian Light Source, Saskatoon

The Canadian Macromolecular Crystallography Facility (CMCF) has hosted an intensive, hands-on synchrotron data collection school annually at the Canadian Light Source since 2011. Our virtual program is spread over two weeks, with participants getting hands-on experience with mentors for all phases of the experimental process, from data collection to processing to structure solution. In 2023, we were joined by special guest Paul Emsley, the primary author of COOT, the world-leading software for macromolecular model-building . Participants attend a series of lectures and are actively engaged in macromolecular crystallography (Mx) data collection at CMCF beamlines. Completing the school enables participants to make effective use of the beamlines remotely, and better equips researchers to collect and analyze diffraction data.

Latest News: MxSchool 2024 registration has not yet opened. Please stay tuned for updates.

General Program

Over the two weeks of the course, the program will include:

  • a series of lectures split over four days spread throughout the course covering sample and experiment preparation, data collection, collection strategies and data reduction,
  • in-depth training to use CMCF beamlines and software,
  • time for each participant to collect data with a mentor, and
  • one-day tutorials covering
    • Data Processing using DIALS, and
    • Model Building with COOT

A more detailed syllabus is provided to participants closer to the school dates.

Conference access

Conference schedules, proceedings, meeting links, and post-meeting videos will be available using Fourwaves. Access for the 2024 proceedings will be linked here.

Registration Fees

Successful applicants will be responsible for the registration fee of $100 per participant, paid prior to the course. Eligible students may choose to apply for full/partial fee coverage using the Larry Calvert travel grant.

Past Mx Schools

Sponsors

Canadian Light Source

Mitegen

UofS Sustainability

MxSchool 2023

12th Annual | November 3-November 17, 2023
Virtual Edition

Special Topic: COOT structure solution and refinement with developer Paul Emsley (MRC Laboratory of Molecular Biology).

Agenda (for participants only)


11th Annual | November 18-December 2, 2022
Virtual Edition

Special Topic: Structure solution using PHENIX by Nigel Moriarty (LBNL) and the PHENIX developer team.

Agenda (for participants only)


MxSchool 2020

10th Annual | November 12-13, 2020
Virtual Edition


MxSchool 2019

9th Annual | June 25-29, 2019
Special Topic: Structure Solution with Dr. Brian Mark, University of Manitoba


MxSchool 2018

8th Annual | June 4-8, 2018
Special Topic: Structure Solution with Dr. Brian Mark, University of Manitoba


MxSchool 2017

7th Annual | June 5-9, 2017
Special Topic: Structure Solution with Dr. Jeffrey Lee, University of Toronto


MxSchool 2016

6th Annual | May 24-28, 2016
Special Topic: Molecular Replacement & COOT with Dr. Jeffrey Lee, University of Toronto


MxSchool 2015

5th Annual | June 2-6, 2015
Special Topic: Phenix / Structure Solution with Dr. Paul Adams, Lawrence Berkeley Laboratory


MxSchool 2014

4th Annual | June 9-13, 2014
Special Topic: Molecular Replacement, Structure Validation & COOT with Dr. Trevor Moraes, University of Toronto


MxSchool 2013

3rd Annual | June 10-14, 2013
Special Topic: Phenix / Structure Solution with Dr. Paul Adams, Lawrence Berkeley Laboratory


MxSchool 2012

2nd Annual | June 5-9, 2012
Special Topic: COOT / Structure Solution & Modeling with Dr. Trevor Moraes, University of Toronto


MxSchool 2011

1st Annual | May 16-20, 2011
Special Topic: Phenix / Structure Solution with Dr. Paul Adams, Lawrence Berkeley Laboratory