Mx Data Collection School

Canadian Light Source, Saskatoon

The Canadian Macromolecular Crystallography Facility (CMCF) has hosted an intensive, hands-on synchrotron data collection school annually at the Canadian Light Source since 2011. Our virtual program is spread over two weeks, with participants getting hands-on experience with mentors for all phases of the experimental process, from data collection to processing to structure solution. In 2023, we were joined by special guest Paul Emsley, the primary author of COOT, the world-leading software for macromolecular model-building . Participants attend a series of lectures and are actively engaged in macromolecular crystallography (Mx) data collection at CMCF beamlines. Completing the school enables participants to make effective use of the beamlines remotely, and better equips researchers to collect and analyze diffraction data.

Latest News: Due to facility upgrades, the MxSchool will not be held in 2024. Please stay tuned for update about 2025.

General Program

Over the two weeks of the course, the program will include:

• a series of lectures split over four days spread throughout the course covering sample and experiment preparation, data collection, collection strategies and data reduction,
• in-depth training to use CMCF beamlines and software,
• time for each participant to collect data with a mentor, and
• one-day tutorials covering
  • Data Processing using DIALS, and
  • Model Building with COOT

A more detailed syllabus is provided to participants closer to the school dates.

Conference access

Conference schedules, proceedings, meeting links, and post-meeting videos will be available using Fourwaves. Access to the 2024 proceedings will be linked here.

Registration Fees

Successful applicants will be responsible for the registration fee of $100 per participant, paid prior to the course. Eligible students may choose to apply for full/partial fee coverage using the Larry Calvert travel grant.

Past Mx Schools

Sponsors

12^th Annual | November 3-November 17, 2023
Virtual Edition

Special Topic: COOT structure solution and refinement with developer Paul Emsley (MRC Laboratory of Molecular Biology).

Agenda (for participants only)

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11^th Annual | November 18-December 2, 2022
Virtual Edition

Special Topic: Structure solution using PHENIX by Nigel Moriarty (LBNL) and the PHENIX developer team.

Agenda (for participants only)

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10^th Annual | November 12-13, 2020
Virtual Edition

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9^th Annual | June 25-29, 2019
Special Topic: Structure Solution with Dr. Brian Mark, University of Manitoba

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8^th Annual | June 4-8, 2018
Special Topic: Structure Solution with Dr. Brian Mark, University of Manitoba

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7^th Annual | June 5-9, 2017
Special Topic: Structure Solution with Dr. Jeffrey Lee, University of Toronto

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6^th Annual | May 24-28, 2016
Special Topic: Molecular Replacement & COOT with Dr. Jeffrey Lee, University of Toronto

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5^th Annual | June 2-6, 2015
Special Topic: Phenix / Structure Solution with Dr. Paul Adams, Lawrence Berkeley Laboratory

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4^th Annual | June 9-13, 2014
Special Topic: Molecular Replacement, Structure Validation & COOT with Dr. Trevor Moraes, University of Toronto

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3^rd Annual | June 10-14, 2013
Special Topic: Phenix / Structure Solution with Dr. Paul Adams, Lawrence Berkeley Laboratory

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2^nd Annual | June 5-9, 2012
Special Topic: COOT / Structure Solution & Modeling with Dr. Trevor Moraes, University of Toronto

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1^st Annual | May 16-20, 2011
Special Topic: Phenix / Structure Solution with Dr. Paul Adams, Lawrence Berkeley Laboratory